Comparative Study on the Extraction of Crude Fucoidan from Brown Seaweed using Conventional, Microwave and Ultrasound-Assisted Methods

Afif Dwijayanto (1), Ahmed Mahmood Abdulhameed Abdullah Al-Yousefi (2), Ifa Puspasari (3), Masturah Markom (4)
(1) Department of Chemical Engineering, Faculty of Industrial Technology, Universitas Islam Indonesia, Yogyakarta., Indonesia
(2) Department of Chemical Engineering, Faculty of Industrial Technology, Universitas Islam Indonesia, Yogyakarta., Indonesia
(3) Department of Chemical Engineering, Faculty of Industrial Technology, Universitas Islam Indonesia, Yogyakarta., Indonesia
(4) Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, The National University of Malaysia, 43600 UKM, Bangi Selangor, Malaysia
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How to cite (AJARCDE) :
Dwijayanto, A., Al-Yousefi, A. M. A. A., Puspasari, I., & Markom, M. (2025). Comparative Study on the Extraction of Crude Fucoidan from Brown Seaweed using Conventional, Microwave and Ultrasound-Assisted Methods. AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment), 9(1), 1–6. https://doi.org/10.29165/ajarcde.v9i1.570

Brown seaweeds are rich in fucoidan, a sulfated polysaccharide with antimicrobial, immunomodulatory, antioxidant, and anticancer properties. The brown algae Sargassum sp. has not been thoroughly investigated for fucoidan extraction using various techniques and evaluations of their effects on extraction yield and its structural properties. The purpose of this study was to compare the structural characteristics and extraction yield of fucoidan from Sargassum sp. using conventional, microwave, and ultrasonic-assisted extraction methods. The results showed that a slightly higher yield was obtained by using the ultrasonic-assisted extraction method (2.772%) followed by the microwave-assisted extraction method (2.494%) and conventional extraction method (2.399%). However, the IC50 values for antioxidants were found to be lower (less value is preferable) for crude fucoidan obtained by microwave-assisted extraction method (175 ?g/ml) than for conventional (195 ?g/ml) and ultrasound-assisted extraction methods (230 ?g/ml). The crude fucoidan obtained from the three different extraction methods showed moderate antioxidant strength


Contribution to Sustainable Development Goals (SDGs)
SDG 3: Good Health and Well-being
SDG 9: Industry, Innovation, and Infrastructure
SDG 12: Responsible Consumption and Production
DG 14: Life Below Water

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